ACTIVATION

Brief summary: 

Activation is a prospective randomised (1 :1) controlled study to test the hypothesis that revascularisation of significant coronary artery disease by Percutaneous Coronary Intervention prior to Transcatheter Aortic Valve Implantation (TAVI) will result in rate of mortality and re-hospitalisation at 12 months that is non-inferior to TAVI without such revascularisation.

Primary endpoints:

Composite of mortality and rehospitalisation at 12 months

CERC Services:

Clinical trial documentation,

Regulatory submissions,

Set-up activities,

eCRF / data-management,

Monitoring,

CEC,

DSMB,

Clinical report

Countries:

France, Germany, United Kingdom

Center number :

17 investigational centers