ACTIVATION

Brief summary

Activation is a prospective randomised (1 :1) controlled study to test the hypothesis that revascularisation of significant coronary artery disease by Percutaneous Coronary Intervention prior to Transcatheter Aortic Valve Implantation (TAVI) will result in rate of mortality and re-hospitalisation at 12 months that is non-inferior to TAVI without such revascularisation.

 

Primary endpoints

Composite of mortality and rehospitalisation at 12 months

 

CERC Services

Clinical trial documentation,

Regulatory submissions,

Set-up activities,

eCRF / data-management,

Monitoring,

CEC,

DSMB,

Clinical report

 

Countries

France, Germany, United Kingdom

 

Centers number

17 investigational centers