Writing session with O. Varenne & C. Dupic

Writing session with

O. Varenne & C. Dupic

Brief summary

The main objective of the SENIOR study is to establish the efficacy and safety of the everolimus eluting stent with a biodegradable abluminal polymer (SYNERGY II) associated with a short dual antiplatelet therapy (DAPT) in patients ≥75 years old, suffering from stable angina, silent ischemia (1 month DAPT) or acute coronary syndromes (6 months DAPT) related to significant coronary artery disease and requiring percutaneous coronary intervention.

Primary endpoints

  • Composite rate of Major Cardiovascular and Cerebrovascular Events (all-cause death, myocardial infarction, stroke, ischemia-driven target lesion revascularization) at one year

CERC Services

  • Full Services including Corelab, CEC & DSMB Management – CERIC Sponsor


Belgium, Finland, France, Italy, Latvia, Macedonia, Spain, Switzerland and UK managed by CERC.

Center number

43 centers managed by CERC.

Lastest News

  • Primary Endpoint results at TCT 2017 by Prof Olivier Varenne and simultaneous publication in Lancet.

Presentation of results : Late Breaking Trial at TCT 2017 (Colorado Convention Center, Denver, Colorado)Session : Main Arena III,

Title: SENIOR: A Randomized Trial of a Bioresorbable Polymer-Based Metallic DES vs a BMS with Short DAPT in Patients With Coronary Artery Disease Older than 75 Years

Date: Wednesday, November 1st, 2017 | 11:00:00 AM – 11:12:00 AM


  • Investigator meeting : Tuesday 31st october

Study Protocol